JHU 37152
CAS No. 2369979-67-7
JHU 37152 ( —— )
Catalog No. M24084 CAS No. 2369979-67-7
JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.?
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 72 | In Stock |
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10MG | 125 | In Stock |
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25MG | 259 | In Stock |
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50MG | 403 | In Stock |
|
100MG | 592 | In Stock |
|
200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameJHU 37152
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NoteResearch use only, not for human use.
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Brief DescriptionJHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.?
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DescriptionJHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.?And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorM3 mAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number2369979-67-7
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Formula Weight358.9
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Molecular FormulaC19H20ClFN4
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Purity>98% (HPLC)
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SolubilityDMSO:72 mg/mL (200.65 mM);Ethanol:24 mg/mL (66.88 mM)
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SMILESFC1=C2C(NC3=CC=C(Cl)C=C3N=C2N4CCN(CC)CC4)=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Anisotropine Methylb...
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
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Decamethonium bromid...
Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
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2,3-Dihydrobenzofura...
2,3-Dihydrobenzofuran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara.?Coumaran can be used as a biopesticide.?2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran.?It has a role as a metabolite.The in vitro inhibition of acetylcholinesterase was increased with the concentration of Coumaran in the housefly (head and thorax) homogenate.